Addiction, POMC Peptide, Can Anyone Direct me to a Good Explaination?



Answers:
I don't know what level of neuropsych understanding you have (or what level of answer you are looking for) but here are a few sites.

http://www.isbra2006.com/abstract/150.htm

"POMC, but not Pdyn-/- mice had a lower preference for alcohol compared to wild type animals during long-term ethanol consumption."

http://en.wikipedia.org/wiki/Endorphin
"Mu receptors are presynaptic, and inhibit neurotransmitter release; through this mechanism, they inhibit the release of the inhibitory neurotransmitter GABA, and disinhibit the dopamine pathways, causing more dopamine to be released. By hijacking this process, exogenous opioids cause inappropriate dopamine release, and lead to aberrant synaptic plasticity which causes addiction."

http://biolog-e.ls.biu.ac.il/synapse/uploads8/5._Opiates.pdf

http://www.winternet.com/~briminst/8026GewirtzHandout.pdf


Explain what? You need to re-do your question.
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