do painkillers have any effect on bone during orthodontic treatment(like delaying deposition/resorption 4 ex.)

actually i heard that from an orthodontist but i looked 4 it everywhere and couldn't find such a thing..so did anyone hear about it?

Answers:
Most of the stuff I can see seems to be related to Non Steroidal Anti Inflammatory medications (ibuprofen, indomethacin, and the like) and COX2 inhibitors (celecoxib, rofecoxib etc)

Furthermore, most of the stuff says that there is no clear evidence that they do.

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